Hepatoma arterial-embolisation (HAP) Score
HAP Score is a simple score which stratifies, patient with with HCC, who will receive their first TACE. It has 4 prognostic factors
Liver related variables – albumin and bilirubin
Tumor related variables- AFP (alpha-fetoprotein), and tumor size
Patients are then categorizes into low-, intermediate-, high-, and very high-risk groups with average survival of 27.6, 18.5, 9.0, and 3.6 months respectively.¹
Prognostic Factors
Albumin < 36 g/dL
AFP > 400 ng/ml
Bilirubin > 17 µmol/L
Maximum Tumor Diameter > 7 cm
Points
1
1
1
1
HAP Classification
HAP A
HAP B
HAP C
HAP D
Points
0
1
2
> 2
Patients with a HAP score of C or D were classified into poor prognosis groups. These groups were unlikely to derive significant benefits from transarterial chemoembolization (TACE) and may instead benefit more from systemic therapy or supportive care.¹
- Kadalayil L, Benini R, Pallan L, O’beirne J, Marelli L, Yu D, Hackshaw A, Fox R, Johnson P, Burroughs AK, Palmer DH. A simple prognostic scoring system for patients receiving transarterial embolisation for hepatocellular cancer. Annals of oncology. 2013 Oct 1;24(10):2565-70.