Evaluation of Liver Function | Child-Turcotte-Pugh (CTP) scores 5-7 or 8-9 | CTP scores 5-7 or 8-9 | CTP scores <9 or 9 |
Tumor Burden Assessment | Based on ‘up-to-7’ criteria | Based on ‘up-to-7’ criteria | Follows the 4 lesions ≤7 cm rule |
Number of Subcategories | B1-4 and quasi C | B1-3, B3 subdivided into B3A and B3B | 3 |
Overlap with BCLC C Class | B4 - Minor impairments of performance status quasi C - segmental or sub-segmental tumor thrombosis | None | None |
Differentiation in Prognosis | Yes | Yes | Yes |
Treatment Aim per Sub-Stage | Not defined | Curative or palliative intent specified | Not defined |
First-Line Treatment Recommendation | TACE and BSC for B4 | Range of options, no specific recommendation | TACE appropriateness |
Availability of Other Treatment Options | Yes | Not specified | No |