Sub-Classification for BCLC

SubClassification for BCLC

Criteria/System	Bolondi System	Kinki Criteria	Japanese Society for Transcatheter Hepatic Arterial Embolization System
Evaluation of Liver Function	Child-Turcotte-Pugh (CTP) scores 5-7 or 8-9	CTP scores 5-7 or 8-9	CTP scores <9 or 9
Tumor Burden Assessment	Based on ‘up-to-7’ criteria	Based on ‘up-to-7’ criteria	Follows the 4 lesions ≤7 cm rule
Number of Subcategories	B1-4 and quasi C	B1-3, B3 subdivided into B3A and B3B	3
Overlap with BCLC C Class	B4 - Minor impairments of performance status quasi C - segmental or sub-segmental tumor thrombosis	None	None
Differentiation in Prognosis	Yes	Yes	Yes
Treatment Aim per Sub-Stage	Not defined	Curative or palliative intent specified	Not defined
First-Line Treatment Recommendation	TACE and BSC for B4	Range of options, no specific recommendation	TACE appropriateness
Availability of Other Treatment Options	Yes	Not specified	No

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