SubClassification for BCLC

Criteria/SystemBolondi SystemKinki CriteriaJapanese Society for Transcatheter Hepatic Arterial Embolization System
Evaluation of Liver FunctionChild-Turcotte-Pugh (CTP) scores 5-7 or 8-9CTP scores 5-7 or 8-9CTP scores <9 or 9
Tumor Burden AssessmentBased on ‘up-to-7’ criteriaBased on ‘up-to-7’ criteriaFollows the 4 lesions ≤7 cm rule
Number of SubcategoriesB1-4 and quasi CB1-3, B3 subdivided into B3A and B3B3
Overlap with BCLC C ClassB4 - Minor impairments of performance status quasi C - segmental or sub-segmental tumor thrombosisNoneNone
Differentiation in PrognosisYesYesYes
Treatment Aim per Sub-StageNot definedCurative or palliative intent specifiedNot defined
First-Line Treatment RecommendationTACE and BSC for B4Range of options, no specific recommendationTACE appropriateness
Availability of Other Treatment OptionsYesNot specifiedNo
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