Percutaneous cholecystostomy

Dr. Ali Asgar Sabir

Percutaneous cholecystostomy (PC) stands as a vital procedure in the treatment of acute cholecystitis (AC), particularly for patients who may not immediately undergo laparoscopic cholecystectomy. Administered by interventional radiologists, PC offers an effective means of decompressing the gallbladder in cases of AC. This intervention encompasses various approaches, including percutaneous transhepatic gallbladder drainage, percutaneous transperitoneal gallbladder drainage, and percutaneous transhepatic gallbladder aspiration. Originating in the 1970s for cases of obstructive jaundice, PC gradually found application in AC during the 1980s. 

Presently, it serves as a viable alternative for individuals unfit for immediate surgical intervention due to factors like severe sepsis, shock, or significant comorbidities. Notably, the World Society of Emergency Surgery (WSES) guidelines endorse PC as a valid option in such scenarios, reinforcing its importance in the realm of emergency medicine.

Indications and contraindications of percutaneous cholecystostomy:

IndicationsContraindications
Patients unsuitable for immediate laparoscopic cholecystectomy due to severe sepsis, shock, or multiple comorbiditiesCoagulopathy (correctable with transfusions)
AC patients not fit for emergency cholecystectomyAllergy to iodinated contrast (ultrasound-guided PC an option)
AC patients with severe comorbidities (per WSES guidelines)Ascites (can be treated with paracentesis prior to PC)
Gallbladder tightly packed with gallstones

Approach for percutaneous cholecystostomy:

TechniqueAdvantagesConsiderations
Transhepatic (most commonly used)1. More anatomic fixation
2. Direct penetration of liver
1. May be unsuitable for distended gallbladders
2. Technical difficulties in some cases
Transperitoneal1. Suitable for patients with distended gallbladders directly adhering to abdominal wall
2. Beneficial in cases with coagulopathy or liver metastasis
3. Debate ongoing, choice depends on patient anatomy
1. Higher risk of complications like bile leakage and recurrence of cholecystitis
2. Right colon may pose challenges
3. Technically more difficult

Patient investigation, procedure and post-procedure care in percutaneous cholecystostomy:

ParametersKeypoints
Coagulation abnormalitiesCorrect prior to procedure (platelets >50,000, INR <1.5)
Prophylactic antibioticsAdministered 12-24 hours before procedure
Imaging ReviewCross-sectional MR and CT images evaluated for anatomy
UltrasoundUsed to examine gallbladder wall thickening and bowel interference
SedationIV midazolam and fentanyl can be used for conscious sedation
PunctureAccess needle (22-18 gauge) used to puncture gallbladder
ConfirmationBile aspiration or contrast injection under fluoroscopy
Drain Insertion8 or 10F drain catheter with multiple side holes for drainage
DecompressionBile sent for cultures and catheter left for gravity drainage
CholecystogramOptional at the time of the procedure if using fluoroscopy
CholecystographyDone at a later date recommended to evaluate catheter position and cystic duct patency
Tube PreservationSome authors advocate tube preservation until surgery
Routine ReplacementsNecessary to prevent malfunction or obstruction of the drainage tube
Tube RemovalIncreasing evidence supports removal after AC resolution
Tract MaturityTract matures in 3-4 weeks, preventing bile leakage
Impact on RecurrenceProlonged tube indwelling a factor for recurrent biliary events
Clinical OutcomesRemoval has no significant impact on outcomes

Complications related to percutaneous cholecystostomy:

ComplicationsDescription
Time to ImprovementMedian of 3-4 days after Percutaneous drain insertion
Minor ComplicationsTube dislodgement (4.5-15%) - most common minor complication,
Minor bleeding (0-1.2%)
Other ComplicationsPneumothorax,
Abscess formation,
Bowel injury,
Bile leak with or without peritonitis (rare)
Major ComplicationsMortality (0-1.4%),
Sepsis (0.9%) - managed by peri-procedure antibiotic management,
Significant bleeding requiring transfusion, embolization or immediate laparotomy
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