ALBI (Albumin-Bilirubin) Score
The ALBI (Albumin-Bilirubin) score is a tool used to assess the severity of liver disease and predict the prognosis of patients with liver cancer. It combines two important markers: albumin and bilirubin. The higher the score, the more advanced the liver disease and the poorer the prognosis.
ALBI score = (log10 bilirubin (μmol/L) x 0.66) + (albumin (g/L) x -0.085)
Based on the ALBI score, patients can be classified into three categories:
ALBI grade 1 ≤ -2.60 (best prognosis),
ALBI grade 2 more than -2.60 to ≤ -1.39 , and
ALBI grade 3 more than -1.39 (worst prognosis). ¹
- Johnson PJ, Berhane S, Kagebayashi C, Satomura S, Teng M, Reeves HL, O’Beirne J, Fox R, Skowronska A, Palmer D, Yeo W. Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach—the ALBI grade. Journal of Clinical Oncology. 2015 Feb 2;33(6):550.
- Karademir S. Staging of hepatocellular carcinoma. Hepatoma Res. 2018;4:58.
- Kinoshita, Akiyoshi et al. “Staging systems for hepatocellular carcinoma: Current status and future perspectives.” World journal of hepatology vol. 7,3 (2015): 406-24. doi:10.4254/wjh.v7.i3.406