Hepatoma arterial-embolisation (HAP) Score

HAP Score is a simple score which stratifies, patient with with HCC, who will receive their first TACE. It has 4 prognostic factors 

Liver related variables – albumin and bilirubin 

Tumor related variables-  AFP (alpha-fetoprotein), and tumor size 

Patients are then categorizes into low-, intermediate-, high-, and very high-risk groups with average survival of 27.6, 18.5, 9.0, and 3.6 months respectively.¹

Prognostic Factors

Albumin < 36 g/dL

AFP  > 400 ng/ml

Bilirubin > 17 µmol/L

Maximum Tumor Diameter > 7 cm

Points

1

1

1

1

HAP Classification

HAP A

HAP B

HAP C

HAP D

Points

0

1

2

> 2

Patients with a HAP score of C or D were classified into poor prognosis groups. These groups were unlikely to derive significant benefits from transarterial chemoembolization (TACE) and may instead benefit more from systemic therapy or supportive care.¹

  1. Kadalayil L, Benini R, Pallan L, O’beirne J, Marelli L, Yu D, Hackshaw A, Fox R, Johnson P, Burroughs AK, Palmer DH. A simple prognostic scoring system for patients receiving transarterial embolisation for hepatocellular cancer. Annals of oncology. 2013 Oct 1;24(10):2565-70.
Skip to content